Md. Wirla Pontes: From Volunteer to Leader in One of the World’s Most Innovative Laboratories

Determination, resilience, and scientific excellence define the journey of Brazilian biomedical scientist Md. Wirla Pontes. Nearly nine years ago, she arrived in the United States with just $5,000 in her pocket and her 11-year-old daughter by her side, determined to start over.
Today, she serves as the director of the laboratory led by the renowned Md. Alysson Muotri at the University of California, San Diego (UCSD), one of the top five universities in the world. Leading a team of 40 researchers, she contributes to groundbreaking advances in neuroscience, stem cells, and space exploration.

Her move to the United States came at a challenging moment. After the end of her marriage, Wirla decided to transform her life and her daughter’s. She began as a volunteer at Md. Alysson Muotri’s laboratory—one of the most prestigious at UCSD—and quickly stood out for her dedication and expertise.

Her talent did not go unnoticed: after a rigorous selection process, she secured a permanent position at the institution.

“I went through a very difficult phase at the end of my marriage and decided to start over. I came here with $5,000 and my 11-year-old daughter, certain that we would succeed,” Wirla recalls, emotionally.

The Muotri Lab is a global leader in innovative research using brain organoids—miniature brains grown in the lab—revolutionizing the study of diseases like autism and Alzheimer’s and paving the way for personalized therapies.

As director, Wirla manages a multicultural team of 40 researchers, ensuring that the lab operates with maximum efficiency and continues to produce high-impact science.

“Our laboratory is international, and one of the biggest challenges is connecting the diverse cultures we have here. We work with researchers from all over the world, always seeking innovative solutions for humanity,” Wirla highlights.

Beyond her work in the lab, Wirla Pontes has become a key figure for the Brazilian scientific diaspora in Southern California. She plays a crucial role in connecting Brazilian and American researchers, facilitating international collaborations, and advancing Brazilian science.

Her work has been instrumental in integrating Brazilian scientists into the project that sends brain organoids to the International Space Station (ISS), putting Brazil on the map of cutting-edge space research.

“Wirla is an exceptional leader and an inspiration to all of us. Her ability to bring together different cultures and people is essential to the success of our laboratory,” says Md. Alysson Muotri.

Over the 16 years of the Muotri Lab’s existence, more than 200 Brazilian researchers have passed through the laboratory—many of them mentored or supported by Wirla. Her journey reinforces the potential of Brazilian science and the importance of investing in national talent.

Today, Wirla Pontes not only leads one of the world’s most innovative laboratories but also inspires young scientists—especially women—to pursue their dreams, no matter the challenges.

Her story proves that with determination and support, it is possible to turn adversity into opportunity and contribute to a better future through science.
Dr. Alysson Muotri’s laboratory at UCSD is a global reference in neuroscience, stem cells, and brain organoid research. Its discoveries continue to revolutionize the understanding of neurological diseases and drive innovative new therapies.